The Dodgers trailed 11-8 getting into the ninth inning after blowing an early five-run lead.
Andy Pages and Kiké Hernández hit consecutive run-scoring doubles to open the ninth inning in opposition to Kevin Ginkel (0-1). Max Muncy tied it at 11-all with a run-scoring single and Ryan Thompson changed Ginkel to face Ohtani.
Ohtani, who doubled twice, fell right into a 1-2 gap earlier than launching his twelfth homer close to the pool deck in proper to place the Dodgers up 14-11. He completed with 4 RBIs.
Tanner Scott labored an ideal ninth save in 11 possibilities.
The Dodgers roughed up Eduardo Rodriguez to take an 8-3 lead by way of three innings, however could not maintain it.
Lourdes Gurriel Jr. hit a tying grand slam within the fifth inning, then Ketel Marte and Randal Grichuk hit solo photographs off Alex Vesia (1-0) within the eighth to place Arizona up 11-8.
Pages completed with three RBIs and Hernández prolonged the Dodgers’ homer streak to 13 straight video games with a solo shot within the second inning.
Marte homered twice for the Diamondbacks. Rodriguez allowed eight runs on 9 hit in 2 2/3 innings.
Ohtani has a knack for coming by way of in huge moments and positive had one in opposition to the Diamondbacks together with his three-run homer within the ninth.
The Diamondbacks hit grand slams in consecutive video games for the second time in crew historical past after Gabriel Moreno hit one Thursday. Arizona additionally did it in opposition to the Dodgers in 2011, by Ryan Roberts and Cole Gillespie.
Dodgers RHP Dusty Might (1-2, 4.36 ERA) faces Diamondbacks RHP Corbin Burnes (1-1, 3.58) within the third sport of the collection on Saturday.